General pharmacology

1.General Pharmacology

Routes of drug administration

1) Two advantages and disadvantages of iv route of drug administration?

Ans)

 

2.         New drug delivery systems?

Ans)

Ø  Ocusert

Ø  Progestasert

Ø Liposomes

Ø Monoclonal antibodies

Ø Drug-eluting stents

Ø  Computerised miniature pumps

 

3.         Advantages of inhalational sublingual routes of drug administration?

Ans) Rapid effect, Low dose is enough so that systemic toxicity can be reduced, Low first pass metabolism and high bioavailability.

 

4.         Trans dermal drug delivery system?

Ans) 

                                                                 Figure 1

 

Examples: Scopolamine patch for motion sickness, Clonidine patch for hypertension

5.         Name two orphan drugs?

Ans) Ivacaftor, Alglucerase